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Issue 23, 2011
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A microfluidic device for self-synchronised production of droplets

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Abstract

The primary requirement for a mixing operation in droplet-based microfluidic devices is an accurate pairing of droplets of reaction fluids over an extended period of time. In this paper, a novel device for self-synchronous production of droplets has been demonstrated. The device uses a change in impedance across a pair of electrodes introduced due to the passage of a pre-formed droplet to generate a second droplet at a second pair of electrodes. The device was characterised using image analysis. Droplets with a volume of ∼23.5 ± 3.1 nl (i.e. ∼93% of the volume of pre-formed droplets) were produced on applying a voltage of 500 V. The synchronisation efficiency of the device was 83%. As the device enables self-synchronised production of droplets, it has a potential to increase the reliability and robustness of mixing operations in droplet-based microfluidic devices.

Graphical abstract: A microfluidic device for self-synchronised production of droplets

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Article information


Submitted
27 Jul 2011
Accepted
06 Oct 2011
First published
21 Oct 2011

Lab Chip, 2011,11, 4052-4056
Article type
Paper

A microfluidic device for self-synchronised production of droplets

R. Gupta, S. J. Baldock, P. Carreras, P. R. Fielden, N. J. Goddard, S. Mohr, B. S. Razavi and B. J. Treves Brown, Lab Chip, 2011, 11, 4052
DOI: 10.1039/C1LC20695H

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