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Issue 21, 2011
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Droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy—concepts and applications

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Abstract

This review outlines concepts and applications of droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy (SERS) as well as the advantages of the approach. Even though the droplet-based flow-through technique is utilized in various fields, the review focuses on implementing droplet-based fluidic systems in Raman and SERS as these highly specific detection methods are of major interest in the field of analytics. With the combination of Raman or SERS with droplet-based fluidics, it is expected to achieve novel opportunities for analytics. Besides the approach of using droplet-based microfluidic devices as a detection platform, the unique properties of flow-through systems for the formation of droplets are capitalized to produce SERS active substrates and to accomplish uniform sample preparation. Within this contribution, previous reported applications on droplet-based flow-through Raman and SERS approaches and the additional benefit with regard to the importance in the field of analytics are considered.

Graphical abstract: Droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy—concepts and applications

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Publication details

The article was received on 15 Jul 2011, accepted on 30 Aug 2011 and first published on 30 Sep 2011


Article type: Critical Review
DOI: 10.1039/C1LC20638A
Citation: Lab Chip, 2011,11, 3584-3592
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    Droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy—concepts and applications

    A. März, T. Henkel, D. Cialla, M. Schmitt and J. Popp, Lab Chip, 2011, 11, 3584
    DOI: 10.1039/C1LC20638A

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