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Issue 17, 2011
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DNA detection with a polymeric nanochannel device

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Abstract

We present the development and the electrical characterization of a polymeric nanochannel device. Standard microfabrication coupled to Focused Ion Beam (FIB) nanofabrication is used to fabricate a silicon master, which can be then replicated in a polymeric material by soft lithography. Such an elastomeric nanochannel device is used to study DNA translocation events during electrophoresis experiments. Our results demonstrate that an easy and low cost fabrication technique allows creation of a low noise device for single molecule analysis.

Graphical abstract: DNA detection with a polymeric nanochannel device

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Publication details

The article was received on 22 Mar 2011, accepted on 02 Jun 2011 and first published on 12 Jul 2011


Article type: Paper
DOI: 10.1039/C1LC20243J
Citation: Lab Chip, 2011,11, 2961-2966
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    DNA detection with a polymeric nanochannel device

    P. Fanzio, V. Mussi, C. Manneschi, E. Angeli, G. Firpo, L. Repetto and U. Valbusa, Lab Chip, 2011, 11, 2961
    DOI: 10.1039/C1LC20243J

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