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Issue 17, 2011
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DNA detection with a polymeric nanochannel device

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Abstract

We present the development and the electrical characterization of a polymeric nanochannel device. Standard microfabrication coupled to Focused Ion Beam (FIB) nanofabrication is used to fabricate a silicon master, which can be then replicated in a polymeric material by soft lithography. Such an elastomeric nanochannel device is used to study DNA translocation events during electrophoresis experiments. Our results demonstrate that an easy and low cost fabrication technique allows creation of a low noise device for single molecule analysis.

Graphical abstract: DNA detection with a polymeric nanochannel device

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Article information


Submitted
22 Mar 2011
Accepted
02 Jun 2011
First published
12 Jul 2011

Lab Chip, 2011,11, 2961-2966
Article type
Paper

DNA detection with a polymeric nanochannel device

P. Fanzio, V. Mussi, C. Manneschi, E. Angeli, G. Firpo, L. Repetto and U. Valbusa, Lab Chip, 2011, 11, 2961
DOI: 10.1039/C1LC20243J

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