Jump to main content
Jump to site search

Issue 10, 2011
Previous Article Next Article

A microfluidic-based hydrodynamic trap: design and implementation

Author affiliations


We report an integrated microfluidic device for fine-scale manipulation and confinement of micro- and nanoscale particles in free-solution. Using this device, single particles are trapped in a stagnation point flow at the junction of two intersecting microchannels. The hydrodynamic trap is based on active flow control at a fluid stagnation point using an integrated on-chip valve in a monolithic PDMS-based microfluidic device. In this work, we characterize device design parameters enabling precise control of stagnation point position for efficient trap performance. The microfluidic-based hydrodynamic trap facilitates particle trapping using the sole action of fluid flow and provides a viable alternative to existing confinement and manipulation techniques based on electric, optical, magnetic or acoustic force fields. Overall, the hydrodynamic trap enables non-contact confinement of fluorescent and non-fluorescent particles for extended times and provides a new platform for fundamental studies in biology, biotechnology and materials science.

Graphical abstract: A microfluidic-based hydrodynamic trap: design and implementation

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 Dec 2010, accepted on 15 Mar 2011 and first published on 08 Apr 2011

Article type: Paper
DOI: 10.1039/C0LC00709A
Citation: Lab Chip, 2011,11, 1786-1794
  •   Request permissions

    A microfluidic-based hydrodynamic trap: design and implementation

    M. Tanyeri, M. Ranka, N. Sittipolkul and C. M. Schroeder, Lab Chip, 2011, 11, 1786
    DOI: 10.1039/C0LC00709A

Search articles by author