Issue 17, 2011
From the journal:

Journal of Materials Chemistry

“Nano-catalyst” for DNA transformation†

Lin Yuan,a   Hongwei Wang,a   Qian Yu,a   Zhaoqiang Wu,a   John L. Brashab  and  Hong Chen*a  

* Corresponding authors

a Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199# Ren'ai Road, Suzhou, China
E-mail: chenh@suda.edu.cn

b Department of Chemical Engineering, McMaster University, Ontario, Canada

Abstract

We introduce poly(N-isopropylacrylamide) decorated silicon nanowire arrays as a novel nano-catalyst for DNA transformation. Almost all of the steps in the transformation process are facilitated by the nano-catalyst, such as DNA acquisition, cell adhesion, DNA transfer, and transformant release. It can promote DNA transformation dramatically and meets the requirements for recombinant DNA operations, including molecular library construction.

Graphical abstract: “Nano-catalyst” for DNA transformation

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Article information

DOI
https://doi.org/10.1039/C1JM10734H
Article type
Communication
Submitted
18 Feb 2011
Accepted
16 Mar 2011
First published
25 Mar 2011

J. Mater. Chem., 2011,21, 6148-6151

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“Nano-catalyst” for DNA transformation

L. Yuan, H. Wang, Q. Yu, Z. Wu, J. L. Brash and H. Chen, J. Mater. Chem., 2011, 21, 6148 DOI: 10.1039/C1JM10734H

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