Issue 14, 2011
From the journal:

Journal of Materials Chemistry

BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9†

Chunyi Zhi,*a   Wenjun Meng,bc   Tomohiko Yamazaki,bc   Yoshio Bando,a   Dmitri Golberg,a   Chengchun Tanga  and  Nobutaka Hanagata*bcd  

* Corresponding authors

a International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Namiki 1-1, Tsukuba, Ibaraki, Japan

b Graduate School of Life Science, Hokkaido University, N10W8, Kita-ku, Sapporo, Japan

c Biomaterials Center, National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba, Ibaraki, Japan

d Nanotechnology Innovation Center, National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba, Ibaraki, Japan

Abstract

For the first time, we demonstrated BN nanospheres (BNNSs) can interact with biomolecules and deliver unmethylated cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) into cells to activate toll-like receptor 9 (TLR9), which is a very important process for therapy of cancers and allergy diseases.

Graphical abstract: BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1JM10199D
Article type
Communication
Submitted
14 Jan 2011
Accepted
08 Feb 2011
First published
07 Mar 2011

J. Mater. Chem., 2011,21, 5219-5222

Permissions

Request permissions

BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9

C. Zhi, W. Meng, T. Yamazaki, Y. Bando, D. Golberg, C. Tang and N. Hanagata, J. Mater. Chem., 2011, 21, 5219 DOI: 10.1039/C1JM10199D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements