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Issue 7, 2011
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Highly efficient Ag(i)-catalyzed regioselective tandem synthesis of diversely substituted quinoxalines and benzimidazoles in water

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Abstract

A green and operationally simple approach for the diverse synthesis of fused quinoxalines and benzimidazoles from o-alkynylaldehydes and amines having an N-tethered nucleophile using Ag(I) as the catalyst in water, is described. The X-ray crystallographic studies confirmed the proposed mechanistic pathway and the cyclized product.

Graphical abstract: Highly efficient Ag(i)-catalyzed regioselective tandem synthesis of diversely substituted quinoxalines and benzimidazoles in water

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The article was received on 31 Mar 2011, accepted on 09 May 2011 and first published on 08 Jun 2011


Article type: Communication
DOI: 10.1039/C1GC15346C
Green Chem., 2011,13, 1640-1643

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    Highly efficient Ag(I)-catalyzed regioselective tandem synthesis of diversely substituted quinoxalines and benzimidazoles in water

    V. Rustagi, T. Aggarwal and A. K. Verma, Green Chem., 2011, 13, 1640
    DOI: 10.1039/C1GC15346C

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