Issue 1, 2011

Synthesis of the natural herbicide δ-aminolevulinic acid from cellulose-derived 5-(chloromethyl)furfural

Abstract

Cellulose-derived 5-(chloromethyl)furfural is converted into δ-aminolevulinic acid in three chemical steps involving conversion to 5-(azidomethyl)furfural, photooxidation, and catalytic hydrogenation in 68% overall yield. δ-Aminolevulinic acid is a natural product with important agrochemical and pharmaceutical applications.

Graphical abstract: Synthesis of the natural herbicide δ-aminolevulinic acid from cellulose-derived 5-(chloromethyl)furfural

Article information

Article type
Communication
Submitted
14 Sep 2010
Accepted
17 Nov 2010
First published
06 Dec 2010

Green Chem., 2011,13, 40-41

Synthesis of the natural herbicide δ-aminolevulinic acid from cellulose-derived 5-(chloromethyl)furfural

M. Mascal and S. Dutta, Green Chem., 2011, 13, 40 DOI: 10.1039/C0GC00548G

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