Issue 4, 2011
From the journal:

Green Chemistry

Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

R. Hartman,*a   R. Helmy,*a   M. Al-Sayaha  and  Christopher J. Welcha  

* Corresponding authors

a Early Development Analytical Research Merck & Co., 126 E Lincoln Ave RY 818 C213, Rahway, New Jersey, USA
E-mail: Roy_Helmy@Merck.com, robert_hartman@merck.com

Abstract

Analytical Method Volume Intensity (AMVI), a simple metric developed to measure the total solvent consumption of an HPLC method, can help chemists make informed decisions on how to lower an analytical method's environmental impact.

Graphical abstract: Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

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Article information

DOI
https://doi.org/10.1039/C0GC00524J
Article type
Paper
Submitted
07 Sep 2010
Accepted
26 Jan 2011
First published
28 Feb 2011

Green Chem., 2011,13, 934-939

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Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

R. Hartman, R. Helmy, M. Al-Sayah and C. J. Welch, Green Chem., 2011, 13, 934 DOI: 10.1039/C0GC00524J

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