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Issue 1, 2011
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Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications

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Abstract

Over the last two decades the layer-by-layer (LbL) assembly technique has become a highly versatile platform for the synthesis of nanoengineered thin films and particles. The widespread need for highly functional and responsive materials for applications in biomedicine—such as drug and gene delivery—has recently led to considerable efforts in the assembly of LbL materials, particularly films that can be subsequently stabilised and functionalised through a range of chemistries. In this tutorial review, recent developments in hydrogen-bonded LbL-assembled materials will be discussed, focusing on the design of materials with enhanced stimuli-responsive characteristics. Emphasis will be given to materials engineered for biomedical applications, specifically films/capsules that afford controlled loading and release of therapeutic cargo for application in vitro and in vivo.

Graphical abstract: Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications

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Publication details

The article was received on 04 Jun 2010 and first published on 30 Sep 2010


Article type: Tutorial Review
DOI: 10.1039/C0CS00001A
Chem. Soc. Rev., 2011,40, 19-29

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    Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications

    G. K. Such, A. P. R. Johnston and F. Caruso, Chem. Soc. Rev., 2011, 40, 19
    DOI: 10.1039/C0CS00001A

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