Jump to main content
Jump to site search

Issue 36, 2011
Previous Article Next Article

Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars

Author affiliations

Abstract

A strategy for the site-specific attachment of 2-deoxy-2-fluorosugars to cysteine and dehydroalanine tagged proteins is reported. When combined with thionation of fluorosugars, such as the widely available 18F probe 2-deoxy-2-[18F]fluoroglucose ([18F]FDG), this methodology allows fast and direct access to site-specific [18F]FDG-labelled proteins.

Graphical abstract: Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars

Back to tab navigation

Supplementary files

Article information


Submitted
14 Jun 2011
Accepted
14 Jul 2011
First published
11 Aug 2011

Chem. Commun., 2011,47, 10010-10012
Article type
Communication

Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars

O. Boutureira, G. J. L. Bernardes, F. D'Hooge and B. G. Davis, Chem. Commun., 2011, 47, 10010
DOI: 10.1039/C1CC13524D

Social activity

Search articles by author

Spotlight

Advertisements