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Issue 26, 2011
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Biochemistry of anionic calix[n]arenes

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This review treats the biological properties of the various anionic calix[n]arenes, both as soluble forms and in the collodal state. The complexation of these molecules with amino-acids, peptides and proteins is discussed, as is their interaction with model membranes. The complexations with various Active Pharmaceutical Ingredients as complexes, for tamoxifen as solid state and colloidal structures, are treated in depth. Two sections deal with the direct biological action of the calix[n]arenes and their use as biosensors. A final section deals with the toxicity, in reality the lack of toxicity of the calix[n]arenes.

Graphical abstract: Biochemistry of anionic calix[n]arenes

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Publication details

The article was received on 17 Mar 2011, accepted on 07 Apr 2011 and first published on 09 May 2011

Article type: Feature Article
DOI: 10.1039/C1CC11541C
Citation: Chem. Commun., 2011,47, 7303-7319

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    Biochemistry of anionic calix[n]arenes

    F. Perret and A. W. Coleman, Chem. Commun., 2011, 47, 7303
    DOI: 10.1039/C1CC11541C

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