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Issue 12, 2011
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Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

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Abstract

SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.

Graphical abstract: Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

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Publication details

The article was received on 30 Nov 2010, accepted on 15 Jan 2011 and first published on 09 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC05265E
Chem. Commun., 2011,47, 3514-3516

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    Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

    K. K. Maiti, A. Samanta, M. Vendrell, K. Soh, M. Olivo and Y. Chang, Chem. Commun., 2011, 47, 3514
    DOI: 10.1039/C0CC05265E

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