Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 7, 2011
Previous Article Next Article

Protein–ligand binding investigated by a single nanoparticleTERS approach

Author affiliations

Abstract

We report TERS imaging of individual 50 nm, biotin-labeled gold nanoparticles bound to a streptavidin-derivatized glass slide. Individual gold nanoparticles detected by a nanoparticle TERS tip generate Raman enhancements in both the biotin and streptavidin signals. These results indicate that nanoparticles are capable of investigating nanoscale spatial and chemical environments with non-resonant Raman enhancements.

Graphical abstract: Protein–ligand binding investigated by a single nanoparticle TERS approach

Back to tab navigation

Supplementary files

Article information


Submitted
19 Nov 2010
Accepted
10 Dec 2010
First published
04 Jan 2011

Chem. Commun., 2011,47, 2065-2067
Article type
Communication

Proteinligand binding investigated by a single nanoparticle TERS approach

S. L. Carrier, C. M. Kownacki and Z. D. Schultz, Chem. Commun., 2011, 47, 2065
DOI: 10.1039/C0CC05059H

Social activity

Search articles by author

Spotlight

Advertisements