Issue 46, 2011
From the journal:

Chemical Communications

A generalized probe selection method for DNA chips†

Satish Balasaheb Nimse,a   Keum-Soo Song,b   Junghoon Kim,b   Van-Thao Ta,a   Van-Thuan Nguyena  and  Taisun Kim*a  

* Corresponding authors

a Institute for Applied Chemistry and Department of Chemistry, Hallym University, Chuncheon, Korea
E-mail: tskim@hallym.ac.kr
Fax: +82-33-256-3421

b Biometrix Technology, Inc., 202 BioVenture Plaza, Chuncheon, Korea

Abstract

The flaws in the present probe selection methods restrained the development of the DNA chip technology and its applications. The presented generalized probe selection method for the DNA chips elaborates the length of the probe, the melting temperatures, the specificity of the probe, and the position where the probe may bind to the targets.

Graphical abstract: A generalized probe selection method for DNA chips

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Article information

DOI
https://doi.org/10.1039/C1CC15137A
Article type
Communication
Submitted
18 Aug 2011
Accepted
15 Sep 2011
First published
06 Oct 2011

Chem. Commun., 2011,47, 12444-12446

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A generalized probe selection method for DNA chips

S. B. Nimse, K. Song, J. Kim, V. Ta, V. Nguyen and T. Kim, Chem. Commun., 2011, 47, 12444 DOI: 10.1039/C1CC15137A

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