Issue 40, 2011
From the journal:

Chemical Communications

Dual colored mesoporous silicananoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity†

Shuqi Wu,‡a   Zhu Li,‡ab   Jiahuai Hanb  and  Shoufa Han*a  

* Corresponding authors

a Department of Chemical Biology, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005, China
E-mail: shoufa@xmu.edu.cn
Tel: +86-0592-2181728

b State Key Laboratory of Cellular Stress Biology and School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, China

Abstract

Alteration of lysosome acidity has been implicated in many biological events ranging from apoptosis to cancer metastasis, etc. Mesoporous silica nanoparticles doped with acid activable rhodamine-lactam and fluorescein isothiocyanate (FITC) were developed for ratiometric sensing of lysosomal pH changes in live cells with flow cytometry.

Graphical abstract: Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC14627K
Article type
Communication
Submitted
28 Jul 2011
Accepted
08 Sep 2011
First published
19 Sep 2011

Chem. Commun., 2011,47, 11276-11278

Permissions

Request permissions

Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity

S. Wu, Z. Li, J. Han and S. Han, Chem. Commun., 2011, 47, 11276 DOI: 10.1039/C1CC14627K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements