Issue 39, 2011
From the journal:

Chemical Communications

Light-induced cytotoxicity of a photochromic spiropyran†

Jesper R. Nilsson,a   Shiming Li,a   Björn Önfelt*bc  and  Joakim Andréasson*a  

* Corresponding authors

a Department of Chemical and Biological Engineering, Physical Chemistry, Chalmers University of Technology, Göteborg, Sweden
E-mail: a-son@chalmers.se
Fax: (+46) 31-772 38 58
Tel: (+46) 31-772 28 38

b Department of Applied Physics, Division of Cell Physics, The Royal Institute of Technology, Stockholm, Sweden

c Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Stockholm, Sweden
E-mail: bjorn.onfelt@ki.se
Fax: (+46) 8-31 11 01

Abstract

In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.

Graphical abstract: Light-induced cytotoxicity of a photochromic spiropyran

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Article information

DOI
https://doi.org/10.1039/C1CC13561A
Article type
Communication
Submitted
15 Jun 2011
Accepted
25 Aug 2011
First published
12 Sep 2011

Chem. Commun., 2011,47, 11020-11022

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Light-induced cytotoxicity of a photochromic spiropyran

J. R. Nilsson, S. Li, B. Önfelt and J. Andréasson, Chem. Commun., 2011, 47, 11020 DOI: 10.1039/C1CC13561A

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