Selective opening of nanoscopic capped mesoporous inorganic materials with nerve agent simulants; an application to design chromo-fluorogenic probes

Inmaculada Candel; Andrea Bernardos; Estela Climent; M. Dolores Marcos; Ramón Martínez-Máñez; Félix Sancenón; Juan Soto; Ana Costero; Salvador Gil; Margarita Parra

doi:10.1039/C1CC12727F

Selective opening of nanoscopic capped mesoporous inorganic materials with nerve agent simulants; an application to design chromo-fluorogenic probes†

Inmaculada Candel,^abc Andrea Bernardos,^abc Estela Climent,^abc M. Dolores Marcos,^abc Ramón Martínez-Máñez,*^abc Félix Sancenón,*^abc Juan Soto,^ab Ana Costero,^ad Salvador Gil^ad and Margarita Parra^ad

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* Corresponding authors

^a Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universidad Politécnica de Valencia – Universidad de Valencia, Spain

^b Departamento de Química, Universidad Politécnica de Valencia, Camino de Vera s/n, Valencia, Spain
E-mail: rmaez@qim.upv.es

^c CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain

^d Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universitat de Valencia, 46100 Burjassot, Valencia, Spain
E-mail: ana.costero@uv.es

Abstract

A hybrid nanoscopic capped mesoporous material, that is selectively opened in the presence of nerve agent simulants, has been prepared and used as a probe for the chromo-fluorogenic detection of these chemicals.

Chemical Communications

Selective opening of nanoscopic capped mesoporous inorganic materials with nerve agent simulants; an application to design chromo-fluorogenic probes†

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Selective opening of nanoscopic capped mesoporous inorganic materials with nerve agent simulants; an application to design chromo-fluorogenic probes

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