Issue 29, 2011
From the journal:

Chemical Communications

Selective labeling of the endoplasmic reticulum in live cells with silicon quantum dots†

Peng Shen,*a   Seiichi Ohta,a   Susumu Inasawa*a  and  Yukio Yamaguchia  

* Corresponding authors

a Department of Chemical System Engineering, Graduate School of Engineering, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, Japan
E-mail: shenpeng@chemsys.t.u-tokyo.ac.jp, inasawa@chemsys.t.u-tokyo.ac.jp
Fax: +81-3-58417303
Tel: +81-3-58412324

Abstract

A simple and novel approach was developed to obtain water-dispersible silicon quantum dots (Si-QDs) of low toxicity that were able to selectively label the endoplasmic reticulum (ER) in live cells. A block copolymer (Pluronic F127) was used to coat the surface of Si-QDs. Si-QDs form aggregates with diameters of 20–40 nm and show an outstanding optical stability upon UV irradiation. Our F127-treated Si-QDs would be a powerful tool for long-term real-time observation of the ER in live cells.

Graphical abstract: Selective labeling of the endoplasmic reticulum in live cells with silicon quantum dots

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Article information

DOI
https://doi.org/10.1039/C1CC12713F
Article type
Communication
Submitted
09 May 2011
Accepted
08 Jun 2011
First published
22 Jun 2011

Chem. Commun., 2011,47, 8409-8411

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Selective labeling of the endoplasmic reticulum in live cells with silicon quantum dots

P. Shen, S. Ohta, S. Inasawa and Y. Yamaguchi, Chem. Commun., 2011, 47, 8409 DOI: 10.1039/C1CC12713F

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