Issue 35, 2011
From the journal:

Chemical Communications

Encoded dendrimers with defined chiral composition via ‘click’ reaction of enantiopure building blocks†

Bahar Yeniad,a   Hemantkumar Naik,a   Roey J. Amir,b   Cor E. Koning,a   Craig J. Hawker*b  and  Andreas Heise*ac  

* Corresponding authors

a Technische Universiteit Eindhoven, Laboratory of Polymer Chemistry, Den Dolech 2, P.O. Box 513, 5600 MB Eindhoven, The Netherlands
E-mail: a.heise@tue.nl

b University of California Santa Barbara, Santa Barbara, USA
E-mail: hawker@mrl.ucsb.edu
Tel: 805-893-7161

c Dublin City University, School of Chemical Sciences, Glasnevin, Dublin 9, Ireland
E-mail: andreas.heise@dcu.ie
Tel: 00353 17006709

Abstract

Dendrimers with end-groups of defined chiral composition have been prepared from alkyne functional enantio-pure building blocks obtained by selective enzymatic (ADH) ketone reductions using click chemistry. Optical rotation and enantioselective enzymatic modification is in agreement with the chiral composition of the dendrimers and permits unique molecular-level encoding of stereoisomeric dendritic libraries.

Graphical abstract: Encoded dendrimers with defined chiral composition via ‘click’ reaction of enantiopure building blocks

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC12434J
Article type
Communication
Submitted
26 Apr 2011
Accepted
08 Jul 2011
First published
26 Jul 2011

Chem. Commun., 2011,47, 9870-9872

Permissions

Request permissions

Encoded dendrimers with defined chiral composition via ‘click’ reaction of enantiopure building blocks

B. Yeniad, H. Naik, R. J. Amir, C. E. Koning, C. J. Hawker and A. Heise, Chem. Commun., 2011, 47, 9870 DOI: 10.1039/C1CC12434J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements