Issue 18, 2011
From the journal:

Chemical Communications

Rhenium(iv) compounds inducing apoptosis in cancer cells†

José Martínez-Lillo,a   Teresa F. Mastropietro,a   Rosamaria Lappano,b   Antonio Madeo,b   Marta E. Alberto,c   Nino Russo,c   Marcello Maggiolinib  and  Giovanni De Munno*a  

* Corresponding authors

a Centro di Eccellenza CEMIF.CAL, Dipartimento di Chimica, Università della Calabria, via P. Bucci 14/c, 87030 Arcavacata di Rende, Cosenza, Italy
E-mail: demunno@unical.it

b Dipartimento Farmaco-Biologico, Università della Calabria, via P. Bucci, 87030 Arcavacata di Rende, Cosenza, Italy

c Dipartimento di Chimica, Università della Calabria, via P. Bucci 14/c, 87030 Arcavacata di Rende, Cosenza, Italy

Abstract

The anticancer properties of a series of mononuclear Re(IV) compounds of formula ReCl4L (where L is bpy = 2,2′-bipyridine; bpym = 2,2′-bipyrimidine; dmbpy = 4,4′-dimethyl-2,2′-bipyridine; phen = 1,10-phenanthroline) were investigated for the first time. All compounds displayed potent in vitro antiproliferative activity against selected cancer cells.

Graphical abstract: Rhenium(iv) compounds inducing apoptosis in cancer cells

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Article information

DOI
https://doi.org/10.1039/C1CC11038A
Article type
Communication
Submitted
22 Feb 2011
Accepted
11 Mar 2011
First published
29 Mar 2011

Chem. Commun., 2011,47, 5283-5285

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Rhenium(IV) compounds inducing apoptosis in cancer cells

J. Martínez-Lillo, T. F. Mastropietro, R. Lappano, A. Madeo, M. E. Alberto, N. Russo, M. Maggiolini and G. De Munno, Chem. Commun., 2011, 47, 5283 DOI: 10.1039/C1CC11038A

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