Issue 31, 2011

LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models

Abstract

A LDL particle functionalized with a GdDO3A-monoamide chelate with a long alkenyl anchor (GdDO3A-OA) was prepared for in vivodetection of atheroplaques. The GdDO3A-OA, when successfully intercalated into the lipid layer of LDL particles, led to a significant enhancement of magnetic resonance imaging signal intensity of atheroplaques in atherosclerosis mouse models.

Graphical abstract: LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models

Supplementary files

Article information

Article type
Communication
Submitted
16 Feb 2011
Accepted
20 Jun 2011
First published
08 Jul 2011

Chem. Commun., 2011,47, 8835-8837

LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models

Y. Yamakoshi, H. Qiao, A. N. Lowell, M. Woods, B. Paulose, Y. Nakao, H. Zhang, T. Liu, S. Lund-Katz and R. Zhou, Chem. Commun., 2011, 47, 8835 DOI: 10.1039/C1CC10924C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements