Issue 7, 2011

Ammonium ylides for the diastereoselective synthesis of glycidic amides

Abstract

A highly trans-selective protocol for the synthesis of glycidic amides was developed. This approach gave access to oxiranes by reacting stabilised ammonium ylides bearing an α-carbonyl group and aromatic aldehydes in moderate to good yields.

Graphical abstract: Ammonium ylides for the diastereoselective synthesis of glycidic amides

Supplementary files

Article information

Article type
Communication
Submitted
05 Nov 2010
Accepted
30 Nov 2010
First published
21 Dec 2010
This article is Open Access

Chem. Commun., 2011,47, 2170-2172

Ammonium ylides for the diastereoselective synthesis of glycidic amides

M. Waser, R. Herchl and N. Müller, Chem. Commun., 2011, 47, 2170 DOI: 10.1039/C0CC04821F

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