Issue 15, 2011
From the journal:

Chemical Communications

“Turn-on” FRET-based luminescent iridium(iii) probes for the detection of cysteine and homocysteine†

Hoi-Yan Shiu,a   Man-Kin Wong*b  and  Chi-Ming Che*a  

* Corresponding authors

a Department of Chemistry, State Key Laboratory on Synthetic Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China
E-mail: cmche@hku.hk
Fax: +852 2857-1586

b Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China
E-mail: bcmkwong@inet.polyu.edu.hk
Fax: +852 2364-9932

Abstract

“Turn-on” FRET-based luminescent probes containing iridium(III) complexes for the detection of Cys and Hcy have been designed and synthesized. The relationship between the steric bulk of the probe and the corresponding emission intensity enhancement towards detection of Cys and Hcy has been studied.

Graphical abstract: “Turn-on” FRET-based luminescent iridium(iii) probes for the detection of cysteine and homocysteine

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Article information

DOI
https://doi.org/10.1039/C0CC04288A
Article type
Communication
Submitted
08 Oct 2010
Accepted
22 Feb 2011
First published
14 Mar 2011

Chem. Commun., 2011,47, 4367-4369

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“Turn-on” FRET-based luminescent iridium(III) probes for the detection of cysteine and homocysteine

H. Shiu, M. Wong and C. Che, Chem. Commun., 2011, 47, 4367 DOI: 10.1039/C0CC04288A

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