Issue 10, 2011
From the journal:

Analytical Methods

Separation and structural characterization of a synthetic cannabinoid found in a herbal product using off-line LC-DAD-NMR

Harri Koskela,*a   Ullastiina Hakala,a   Leena Loiske,b   Paula Vanninena  and  Ilmari Szilvayc  

* Corresponding authors

a VERIFIN, University of Helsinki, P.O. Box 55, Helsinki, Finland
E-mail: Harri.T.Koskela@helsinki.fi
Fax: +358 9 191 50437

b Technology and Transport, Helsinki Metropolia University of Applied Sciences, P.O. Box 4000, Helsinki, Finland

c Tullilaboratorio, Finnish Customs, P.O. Box 53, Espoo, Finland

Abstract

A herbal product confiscated by the Finnish Customs was analyzed. No illegal compounds were found in the preliminary GC-MS screening against the mass spectral library. The most prominent compounds in the sample, however, could not be identified. These compounds of interest were characterized using an off-line LC-DAD-NMR technique with a mass-sensitive microcoil probehead. The structural analysis, confirmed by GC-MS and LC-MS studies, revealed the presence of a CP 47,497-C8 type compound with a structural modification in the cyclohexyl part of the compound. The structural modification of this potentially psychoactive compound was presumably intended to elude routine screening.

Graphical abstract: Separation and structural characterization of a synthetic cannabinoid found in a herbal product using off-line LC-DAD-NMR

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Article information

DOI
https://doi.org/10.1039/C1AY05287J
Article type
Paper
Submitted
11 May 2011
Accepted
07 Jul 2011
First published
23 Aug 2011

Anal. Methods, 2011,3, 2307-2312

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Separation and structural characterization of a synthetic cannabinoid found in a herbal product using off-line LC-DAD-NMR

H. Koskela, U. Hakala, L. Loiske, P. Vanninen and I. Szilvay, Anal. Methods, 2011, 3, 2307 DOI: 10.1039/C1AY05287J

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