Issue 21, 2011
From the journal:

Analyst

Hemin/G-quadruplexes as DNAzymes for the fluorescent detection of DNA, aptamer–thrombin complexes, and probing the activity of glucose oxidase

Eyal Golub,a   Ronit Freeman,a   Angelica Niazova  and  Itamar Willner*a  

* Corresponding authors

a Institute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel
E-mail: willnea@vms.huji.ac.il
Fax: +972-2-6527715

Abstract

Hemin/G-quadruplex catalyzes the H2O2-mediated oxidation of Amplex Red to the fluorescent product resorufin. This process is implemented to develop hairpin nucleic acid structures for the detection of DNA, to probe the catalytic activity of glucose oxidase, to use the thrombin–aptamer complex as a catalytic readout structure, and to quantitatively analyze telomere chain composition.

Graphical abstract: Hemin/G-quadruplexes as DNAzymes for the fluorescent detection of DNA, aptamer–thrombin complexes, and probing the activity of glucose oxidase

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C1AN15596B
Article type
Communication
Submitted
14 Jul 2011
Accepted
12 Aug 2011
First published
01 Sep 2011

Analyst, 2011,136, 4397-4401

Permissions

Request permissions

Hemin/G-quadruplexes as DNAzymes for the fluorescent detection of DNA, aptamer–thrombin complexes, and probing the activity of glucose oxidase

E. Golub, R. Freeman, A. Niazov and I. Willner, Analyst, 2011, 136, 4397 DOI: 10.1039/C1AN15596B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements