Issue 12, 2011

Direct detection of RNAs in living cells using peptide-inserted Renillaluciferase

Abstract

In this study, non-engineered RNAs were detected in living cells using bioluminescence. Two types of probe were utilized: a peptide inserted RLuc (PI-RLuc) probe and a split-RNA probe. Incorporation of the PI-RLuc and split-RNA probes enabled the direct detection of RNA introduced into living cells.

Graphical abstract: Direct detection of RNAs in living cells using peptide-inserted Renillaluciferase

Article information

Article type
Communication
Submitted
16 Feb 2011
Accepted
18 Apr 2011
First published
03 May 2011

Analyst, 2011,136, 2446-2449

Direct detection of RNAs in living cells using peptide-inserted Renillaluciferase

T. Andou, T. Endoh, M. Mie and E. Kobatake, Analyst, 2011, 136, 2446 DOI: 10.1039/C1AN15130D

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