Issue 2, 2011
From the journal:

Analyst

Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”

Shen Zheng,a   Abigail Webster,a   Kevin J. Welham,a   Charlotte E. Dyer,b   John Greenmanb  and  Stephen J. Haswell*a  

* Corresponding authors

a Department of Chemistry, Cottingham Road, Hull, UK
E-mail: s.j.haswell@hull.ac.uk
Fax: +44(0)1482466410
Tel: +44(0)1482465469

b Centre for Biomedical Research, University of Hull, Hull, UK

Abstract

Comment by Tsikas et al. (Analyst, 2011, DOI: 10.1039/c0an00411a) on the preliminary work by Shen and colleagues (Analyst, 2010, 135, 302) describing the use of ESI-MS/MS for the detection of methylpiperazinobenzenediamine, as a probe for NO in tissue samples, have been addressed in this communication. The article concludes that the points raised by Tsikas represent a logical progression to the research reported and indicate the way forward in realising appropriate analytical methodology.

Graphical abstract: Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”

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Article information

DOI
https://doi.org/10.1039/C0AN00729C
Article type
Comment
Submitted
17 Sep 2010
Accepted
30 Sep 2010
First published
08 Oct 2010

Analyst, 2011,136, 411-411

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Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”

S. Zheng, A. Webster, K. J. Welham, C. E. Dyer, J. Greenman and S. J. Haswell, Analyst, 2011, 136, 411 DOI: 10.1039/C0AN00729C

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