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Issue 2, 2010
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Electric and electrophoretic inversion of the DNA charge in multivalent electrolytes

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Abstract

Counterion-induced inversion of the DNA charge was characterized through extensive molecular dynamics simulations. We observed reversal of the DNA motion in an external electric field upon increasing the concentration of trivalent or quadrivalent counterions. In the case of a divalent electrolyte, inversion of the DNA's electric charge was observed at high concentrations of the electrolyte but not reversal of the DNA's electrophoretic motion. We demonstrate that inversion of the electrophoretic mobility of the DNA results from a complex interplay of electrostatics and hydrodynamics.

Graphical abstract: Electric and electrophoretic inversion of the DNA charge in multivalent electrolytes

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The article was received on 01 Sep 2009, accepted on 06 Oct 2009 and first published on 21 Oct 2009


Article type: Communication
DOI: 10.1039/B917973A
Soft Matter, 2010,6, 243-246

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    Electric and electrophoretic inversion of the DNA charge in multivalent electrolytes

    B. Luan and A. Aksimentiev, Soft Matter, 2010, 6, 243
    DOI: 10.1039/B917973A

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