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Issue 1, 2010
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Diamine ligands in copper-catalyzed reactions

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The utility of copper-mediated cross-coupling reactions has been significantly increased by the development of mild reaction conditions and the ability to employ catalytic amounts of copper. The use of diamine-based ligands has been important in these advances and in this perspective we discuss these systems, including the choice of reaction conditions and applications in the synthesis of pharmaceuticals, natural products and designed materials.

Graphical abstract: Diamine ligands in copper-catalyzed reactions

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The article was received on 04 Jan 2010, accepted on 29 Mar 2010 and first published on 12 May 2010

Article type: Perspective
DOI: 10.1039/C0SC00107D
Citation: Chem. Sci., 2010,1, 13-31

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    Diamine ligands in copper-catalyzed reactions

    D. S. Surry and S. L. Buchwald, Chem. Sci., 2010, 1, 13
    DOI: 10.1039/C0SC00107D

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