Issue 12, 2010
From the journal:

Photochemical & Photobiological Sciences

Methacrylate monomers lower the level of reduced glutathione and increase the in vitro sensitivity of cells to optical radiation

Terje Christensen*ab  and  Ellen M. Bruzella  

* Corresponding authors

a NIOM – Nordic Institute of Dental Materials, P.O. Box 70, Haslum, Norway
E-mail: terje.christensen@nrpa.no
Fax: (+47) 67147407
Tel: (+47) 67162500

b Norwegian Radiation Protection Authority, Section for Non-Ionising Radiation, P.O. Box 55, Østerås, Norway

Abstract

Induction of cell death by optical radiation in the wavelength range 350–500 nm was significantly increased by commonly used methacrylate monomers, not mediated by absorption of radiation by the methacrylate monomers, but through a mechanism involving rapid reduction in the level of glutathione (GSH).

Graphical abstract: Methacrylate monomers lower the level of reduced glutathione and increase the in vitro sensitivity of cells to optical radiation

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Article information

DOI
https://doi.org/10.1039/C0PP00240B
Article type
Communication
Submitted
30 Jul 2010
Accepted
08 Sep 2010
First published
23 Sep 2010

Photochem. Photobiol. Sci., 2010,9, 1597-1600

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Methacrylate monomers lower the level of reduced glutathione and increase the in vitro sensitivity of cells to optical radiation

T. Christensen and E. M. Bruzell, Photochem. Photobiol. Sci., 2010, 9, 1597 DOI: 10.1039/C0PP00240B

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