Issue 3, 2010

A new protocol in photodynamic therapy: enhanced tumour cell death by combining two different photosensitizers

Abstract

The combined application of two photosensitisers (PSs), zinc(II) phthalocyanine (ZnPc) and the cationic porphyrin meso-tetrakis(4-N-methylpyridyl)porphine (T4MPyP), on HeLa cells produced an enhanced lethal effect relative to treatments with single PSs. Thus, the proper combination of PSs may constitute a new strategy to improve the efficacy of clinical photodynamic therapy.

Graphical abstract: A new protocol in photodynamic therapy: enhanced tumour cell death by combining two different photosensitizers

Additions and corrections

Article information

Article type
Communication
Submitted
02 Nov 2009
Accepted
28 Dec 2009
First published
27 Jan 2010

Photochem. Photobiol. Sci., 2010,9, 295-297

A new protocol in photodynamic therapy: enhanced tumour cell death by combining two different photosensitizers

A. Villanueva, J. C. Stockert, M. Cañete and P. Acedo, Photochem. Photobiol. Sci., 2010, 9, 295 DOI: 10.1039/B9PP00153K

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