Jump to main content
Jump to site search

Issue 19, 2010
Previous Article Next Article

Tellurium: an element with great biological potency and potential

Author affiliations

Abstract

Tellurium has long appeared as a nearly ‘forgotten’ element in Biology, with most studies focusing on tellurite, tellurate and a handful of organic tellurides. During the last decade, several discoveries have fuelled a renewed interest in this element. Bioincorporation of telluromethionine provides a new approach to add heavy atoms to selected sites in proteins. Cadmium telluride (CdTe) nanoparticles are fluorescent and may be used as quantum dots in imaging and diagnosis. The antibiotic properties of tellurite, long known yet almost forgotten, have attracted renewed interest, especially since the biochemical mechanisms of tellurium cytotoxicity are beginning to emerge. The close chemical relationship between tellurium and sulfur also transcends into in vitro and in vivo situations and provides new impetus for the development of enzyme inhibitors and redox modulators, some of which may be of interest in the field of antibiotics and anticancer drug design.

Graphical abstract: Tellurium: an element with great biological potency and potential

Back to tab navigation

Publication details

The article was received on 05 May 2010, accepted on 28 Jun 2010 and first published on 17 Aug 2010


Article type: Emerging Area
DOI: 10.1039/C0OB00086H
Citation: Org. Biomol. Chem., 2010,8, 4203-4216
  •   Request permissions

    Tellurium: an element with great biological potency and potential

    L. A. Ba, M. Döring, V. Jamier and C. Jacob, Org. Biomol. Chem., 2010, 8, 4203
    DOI: 10.1039/C0OB00086H

Search articles by author

Spotlight

Advertisements