Issue 21, 2010
From the journal:

Organic & Biomolecular Chemistry

A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells†

Yi Zhou,a   Xue-Yan You,a   Yuan Fang,a   Ju-Ying Li,a   Ke Liua  and  Cheng Yao*a  

* Corresponding authors

a College of Science and State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, Nanjing 210009, P. R. China
E-mail: yaochengnjut@126.com
Fax: +86-25-8358-7433
Tel: +86-25-8358-7433

Abstract

A rhodamine-based sensor RB-S2 was designed and synthesized by combination of the thiospirolacton chromophore and the thiophen ring block with high affinity to Hg2+. Probe RB-S2 exhibits high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Hg2+ in aqueous solution. In addition, fluorescent imaging of Hg2+ in MCF-7 cells is also successfully demonstrated.

Graphical abstract: A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells

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Article information

DOI
https://doi.org/10.1039/C0OB00452A
Article type
Communication
Submitted
19 Jul 2010
Accepted
03 Sep 2010
First published
22 Sep 2010

Org. Biomol. Chem., 2010,8, 4819-4822

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A thiophen-thiooxorhodamine conjugate fluorescent probe for detecting mercury in aqueous media and living cells

Y. Zhou, X. You, Y. Fang, J. Li, K. Liu and C. Yao, Org. Biomol. Chem., 2010, 8, 4819 DOI: 10.1039/C0OB00452A

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