Issue 21, 2010
From the journal:

Organic & Biomolecular Chemistry

A domino synthesis of benzoquinolinamide in the presence of iodine†

Li-Yan Zenga  and  Chun Cai*a  

* Corresponding authors

a Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, China
E-mail: c.cai@mail.njust.edu.cn
Fax: +86-25-84315030
Tel: +86-25-84315514

Abstract

The domino synthesis of benzo[f]quinolinyl and benzo[h]quinolinyl acetamides from diketene, amines, aromatic aldehydes and naphthalenamine was developed, and the catalyst iodine was found to be crucial to the reaction. The structure was deduced from the mass spectrum, 1H NMR, 13C NMR spectrum and 2D NMR performed on two representative products.

Graphical abstract: A domino synthesis of benzoquinolinamide in the presence of iodine

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Article information

DOI
https://doi.org/10.1039/C0OB00364F
Article type
Communication
Submitted
01 Jul 2010
Accepted
18 Aug 2010
First published
06 Sep 2010

Org. Biomol. Chem., 2010,8, 4803-4805

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A domino synthesis of benzoquinolinamide in the presence of iodine

L. Zeng and C. Cai, Org. Biomol. Chem., 2010, 8, 4803 DOI: 10.1039/C0OB00364F

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