Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]− derivatives

Abstract

CO plays an important role in biological processes and molecules which release CO in a controllable way could therefore be used for medicinal purposes. Beside organometallic carbonyl complexes, boranocarbonate [H₃BCO₂H]⁻ is one of the most promising candidates but releases CO too rapidly. In order to delay the CO release, we have prepared boranocarbamates [H₃BCONH-R]⁻ from [H₃BCO₂H]⁻ which comprise histamine, morpholine, aniline and ethylene-diamine bound via amides to the {H₃BCO} moiety. The syntheses of the new derivatives is described together with their structural characterization. These compounds release CO at a much slower rate than the parent compound and are therefore potential CO releasing molecules for biological and medicinal application.