Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1†
Abstract
Recently, we described the first small-molecule
* Corresponding authors
a
Department of Medicinal Chemistry, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark
E-mail:
krst@farma.ku.dk
Fax: (+45) 3533 6041
Tel: (+45) 3533 6114
b
Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Blegdamsvej 3B, Copenhagen, Denmark
E-mail:
gether@sund.ku.dk
Fax: (+45) 3532 7610
Tel: (+45) 3532 7548
c Risø National Laboratory for Sustainable Energy, Technical University of Denmark, Frederiksborgvej 399, Roskilde, Denmark
d Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, USA
Recently, we described the first small-molecule
A. Bach, N. Stuhr-Hansen, T. S. Thorsen, N. Bork, I. S. Moreira, K. Frydenvang, S. Padrah, S. B. Christensen, K. L. Madsen, H. Weinstein, U. Gether and K. Strømgaard, Org. Biomol. Chem., 2010, 8, 4281 DOI: 10.1039/C0OB00025F
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