Issue 8, 2010

Solid phase synthesis of hydrogen bond surrogate derived α-helices: resolving the case of a difficult amide coupling

Abstract

Solid phase synthesis of HBS helices involving the Fukuyama–Mitsunobu reaction and triphosgene coupling is described.

Graphical abstract: Solid phase synthesis of hydrogen bond surrogate derived α-helices: resolving the case of a difficult amide coupling

Supplementary files

Article information

Article type
Communication
Submitted
15 Jan 2010
Accepted
22 Feb 2010
First published
05 Mar 2010

Org. Biomol. Chem., 2010,8, 1773-1776

Solid phase synthesis of hydrogen bond surrogate derived α-helices: resolving the case of a difficult amide coupling

A. Patgiri, M. R. Witten and P. S. Arora, Org. Biomol. Chem., 2010, 8, 1773 DOI: 10.1039/C000905A

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