Issue 8, 2010

Synthesis of the structure proposed for the natural allenic antibioticscorodonin

Abstract

The structure proposed for scorodonin, a natural allenyne with significant antibacterial and antifungal activities, was synthesized through an enantioselective route. The spectroscopic data of the synthetic allenyne are generally consistent with those reported for the natural one, but slight yet definite differences were observed in 13C NMR.

Graphical abstract: Synthesis of the structure proposed for the natural allenic antibiotic scorodonin

Supplementary files

Article information

Article type
Paper
Submitted
13 Jan 2010
Accepted
08 Feb 2010
First published
26 Feb 2010

Org. Biomol. Chem., 2010,8, 1905-1909

Synthesis of the structure proposed for the natural allenic antibiotic scorodonin

Y. Jian and Y. Wu, Org. Biomol. Chem., 2010, 8, 1905 DOI: 10.1039/C000481B

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