Zn(OTf)2-catalyzed addition of amines to carbodiimides: efficient synthesis of guanidines and unpredicted formation of Zn–N amido species†
Abstract
Zn(OTf)2 acts as an excellent catalyst precursor for addition of various amine N–H bonds to carbodiimides under an atmosphere of air, offering a convenient synthesis of substituted guanidines with high functional-group tolerance. A Zn–N amido species is shown to act as the active species.