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Issue 2, 2010
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Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system

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Abstract

A study of the effect of substrate structure on a Claisen-aza-Cope reaction is presented including a rationalisation of the reaction outcome using DFT calculations. An asymmetric version of the reaction is also described that is of relevance to a proposed approach to the communesin family of natural products.

Graphical abstract: Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system

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Article information


Submitted
31 Jul 2009
Accepted
13 Oct 2009
First published
26 Nov 2009

Org. Biomol. Chem., 2010,8, 442-450
Article type
Paper

Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system

N. Voûte, D. Philp, A. M. Z. Slawin and N. J. Westwood, Org. Biomol. Chem., 2010, 8, 442
DOI: 10.1039/B915677A

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