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Issue 7, 2010
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Ultrasensitive detection of antibodies using a new Tus–Ter-lock immunoPCR system

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Abstract

A system consisting of a protein LG coated surface for the capture of mammalian antibodies (target), and an antigen fused to Tus and stoichiometrically linked to a DNA template via the Tus–Ter-lock sequence allowed the ultrasensitive detection of 5.5 attomol of target by real-time immunoPCR in complex media.

Graphical abstract: Ultrasensitive detection of antibodies using a new Tus–Ter-lock immunoPCR system

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Publication details

The article was received on 01 Feb 2010, accepted on 26 Feb 2010 and first published on 08 Mar 2010


Article type: Communication
DOI: 10.1039/C002163F
Citation: Mol. BioSyst., 2010,6, 1173-1175

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    Ultrasensitive detection of antibodies using a new Tus–Ter-lock immunoPCR system

    I. Morin, N. E. Dixon and P. M. Schaeffer, Mol. BioSyst., 2010, 6, 1173
    DOI: 10.1039/C002163F

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