Jump to main content
Jump to site search

Issue 8, 2010
Previous Article Next Article

Chemistry and biology of orexin signaling

Author affiliations


The orexins are neurohormones that, in concert with their cognate receptors, regulate a number of important physiological processes, including feeding, sleep, reward seeking and energy homeostasis. The orexin receptors have recently emerged as important drug targets. This review provides an overview of recent development in deciphering the biology of orexin signaling as well as efforts to manipulate orexin signaling pharmacologically.

Graphical abstract: Chemistry and biology of orexin signaling

Back to tab navigation

Publication details

The article was received on 23 Feb 2010, accepted on 05 May 2010 and first published on 07 Jun 2010

Article type: Review Article
DOI: 10.1039/C003468A
Mol. BioSyst., 2010,6, 1366-1375

  •   Request permissions

    Chemistry and biology of orexin signaling

    T. Kodadek and D. Cai, Mol. BioSyst., 2010, 6, 1366
    DOI: 10.1039/C003468A

Search articles by author