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Issue 8, 2010
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Chemistry and biology of orexin signaling

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Abstract

The orexins are neurohormones that, in concert with their cognate receptors, regulate a number of important physiological processes, including feeding, sleep, reward seeking and energy homeostasis. The orexin receptors have recently emerged as important drug targets. This review provides an overview of recent development in deciphering the biology of orexin signaling as well as efforts to manipulate orexin signaling pharmacologically.

Graphical abstract: Chemistry and biology of orexin signaling

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Publication details

The article was received on 23 Feb 2010, accepted on 05 May 2010 and first published on 07 Jun 2010


Article type: Review Article
DOI: 10.1039/C003468A
Mol. BioSyst., 2010,6, 1366-1375

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    Chemistry and biology of orexin signaling

    T. Kodadek and D. Cai, Mol. BioSyst., 2010, 6, 1366
    DOI: 10.1039/C003468A

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