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Issue 25, 2010
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Near-infrared absorbing and luminescent gold speckled silica nanoparticles for photothermal therapy

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Abstract

Herein, we report the development and functional evaluation of sub-50 nm near-infrared absorbing and luminescent gold speckled silica (GSS) nanoparticles for fluorescence traceable and selective, in vitro and in vivo photothermal ablation applications. The nanoparticles prepared using microemulsion-mediated approach, are comprised of GRAS (generally regarded as safe) materials, and are promising multifunctional agents for image guided photo-mediated therapies.

Graphical abstract: Near-infrared absorbing and luminescent gold speckled silica nanoparticles for photothermal therapy

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Publication details

The article was received on 08 Feb 2010, accepted on 28 Apr 2010 and first published on 26 May 2010


Article type: Communication
DOI: 10.1039/C0JM00354A
Citation: J. Mater. Chem., 2010,20, 5182-5185
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    Near-infrared absorbing and luminescent gold speckled silica nanoparticles for photothermal therapy

    P. Sharma, S. C. Brown, A. Singh, N. Iwakuma, G. Pyrgiotakis, V. Krishna, J. A. Knapik, K. Barr, B. M. Moudgil and S. R. Grobmyer, J. Mater. Chem., 2010, 20, 5182
    DOI: 10.1039/C0JM00354A

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