Selective encapsulation of dye molecules in dendrimer/polymer multilayer microcapsules by DNA hybridization

Abstract

Using single strand DNA (ssDNA) target as a “vehicle” and Cy5 dye molecule as “cargo”, the selective encapsulation of Cy5 by DNA hybridization in dendrimer/polymer multilayer microcapsules is reported. This approach can be applied for many low molecular weight molecules, which are usually difficult encapsulate because of their diffusion.