Issue 33, 2010
From the journal:

Dalton Transactions

Encapsulation of dual cytotoxic and anti-angiogenic gold(iii) complexes by gelatin-acacia microcapsules: In vitro and in vivo studies†

Jessie Jing Yan,a   Raymond Wai-Yin Sun,a   Peng Wu,a   Marie C. M. Lin,a   Albert S.-C. Chanb  and  Chi-Ming Che*a  

* Corresponding authors

a Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China
E-mail: cmche@hku.hk
Fax: +852 28571586

b Department of Applied Biology and Chemical Technology, Institute of Textiles and Clothing, Hong Kong Polytechnic University, Hong Kong, China

Abstract

Encapsulation of the anticancer gold(III) complexes bearing porphyrin or Schiff-base ligands by gelatin-acacia microcapsules confers both sustained-release and rapid-release properties, improved solution stability and/or in vivo efficacy compared to that using the unencapsulated complexes alone.

Graphical abstract: Encapsulation of dual cytotoxic and anti-angiogenic gold(iii) complexes by gelatin-acacia microcapsules: In vitro and in vivo studies

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Article information

DOI
https://doi.org/10.1039/C003044A
Article type
Paper
Submitted
12 Feb 2010
Accepted
11 May 2010
First published
23 Jul 2010

Dalton Trans., 2010,39, 7700-7705

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Encapsulation of dual cytotoxic and anti-angiogenic gold(III) complexes by gelatin-acacia microcapsules: In vitro and in vivo studies

J. J. Yan, R. W. Sun, P. Wu, M. C. M. Lin, A. S.-C. Chan and C. Che, Dalton Trans., 2010, 39, 7700 DOI: 10.1039/C003044A

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