A dinuclear nickel complex modeling of the Nid(II)-Nip(I) state of the active site of acetyl CoA synthase

Tsuyoshi Matsumoto; Mikinao Ito; Mai Kotera; Kazuyuki Tatsumi

doi:10.1039/B924915J

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A dinuclear nickel complex modeling of the Ni_d(ii)-Ni_p(i) state of the active site of acetyl CoA synthase†

Tsuyoshi Matsumoto,*^a Mikinao Ito,^a Mai Kotera^a and Kazuyuki Tatsumi*^a

Author affiliations

* Corresponding authors

^a Research Center for Materials Science, and Department of Chemistry, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan
E-mail: i45100a@nucc.cc.nagoya-u.ac.jp
Fax: +81 52 789 2943
Tel: +81 52 789 2474

Abstract

The dinuclear Ni(II)-Ni(I) complex Ni^II(dadt^Et)Ni^I(SDmp)(PPh₃) was synthesized as a Ni(II)_d–Ni(I)_p model of the A-cluster in acetyl CoA synthase. This complex was reacted with Co(dmgBF₂)₂(Me)(Py) and KSDmp successively to afford Ni(dadt^Et)Ni(Me)(SDmp), which further reacts with CO to afford the acetylthioester CH₃C(O)SDmp via reductive elimination.

This article is part of the themed collection: Bioinspired catalysis

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/B924915J
Article type: Communication
Submitted: 26 Nov 2009
Accepted: 07 Jan 2010
First published: 19 Jan 2010

Download Citation

Dalton Trans., 2010,39, 2995-2997

Permissions

Request permissions

A dinuclear nickel complex modeling of the Ni_d(II)-Ni_p(I) state of the active site of acetyl CoA synthase

T. Matsumoto, M. Ito, M. Kotera and K. Tatsumi, Dalton Trans., 2010, 39, 2995 DOI: 10.1039/B924915J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Dalton Transactions