Issue 11, 2010

Functional nanoprobes for ultrasensitive detection of biomolecules

Abstract

There has been great interest in developing new nucleic acid and protein detection methods for both clinical and numerous non-clinical applications. In a long-lasting effort to improve the detection ability of bioassays, functional nanomaterials have been actively explored to greatly enhance the sensitivity during the last two decades. This tutorial review focuses on recent progress in biosensor development by exploiting several unique optical, electronic and catalytic properties of a range of nanomaterials, such as gold nanoparticles, quantum dots, silicon nanowires, carbon nanotubes and graphene. In addition, a perspective on new opportunities offered by emerging technologies (e.g. DNA nanotechnology) is provided.

Graphical abstract: Functional nanoprobes for ultrasensitive detection of biomolecules

Article information

Article type
Tutorial Review
Submitted
27 May 2010
First published
24 Sep 2010

Chem. Soc. Rev., 2010,39, 4234-4243

Functional nanoprobes for ultrasensitive detection of biomolecules

S. Song, Y. Qin, Y. He, Q. Huang, C. Fan and H. Chen, Chem. Soc. Rev., 2010, 39, 4234 DOI: 10.1039/C000682N

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