A liposome-based energy conversion system for accelerating the multi-enzyme reactions

Ryuhei Matsumoto; Masaya Kakuta; Taiki Sugiyama; Yoshio Goto; Hideki Sakai; Yuichi Tokita; Tsuyonobu Hatazawa; Seiya Tsujimura; Osamu Shirai; Kenji Kano

doi:10.1039/C0CP00556H

A liposome-based energy conversion system for accelerating the multi-enzyme reactions†‡

Ryuhei Matsumoto,*^a Masaya Kakuta,^a Taiki Sugiyama,^a Yoshio Goto,^a Hideki Sakai,^a Yuichi Tokita,*^a Tsuyonobu Hatazawa,^a Seiya Tsujimura,^b Osamu Shirai^b and Kenji Kano*^b

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* Corresponding authors

^a Advanced Materials Laboratories, Sony Corporation, Atsugi-shi, Japan
E-mail: Yuichi.Tokita@jp.sony.com
Fax: +81 46 226 2405
Tel: +81 46 226 2077

^b Division of Applied Life Scicences, Graduate School of Agriculture, Kyoto University, Sakyo-ku Kyoto 606-8224, Japan
E-mail: kkano@kais.kyoto-u.ac.jp

Abstract

We report the first example of a liposome-based energy conversion system that is useful for entrapping enzymes and NAD coenzyme to accelerate multi-step enzymatic reactions. The liposome generates a much higher catalytic current compared with the non-liposome system, which is in good consistency with numerical simulations.

Physical Chemistry Chemical Physics

A liposome-based energy conversion system for accelerating the multi-enzyme reactions†‡

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A liposome-based energy conversion system for accelerating the multi-enzyme reactions

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