Issue 5, 2010

Characterisation of amorphous and nanocrystalline molecular materials by total scattering

Abstract

The use of high-energy X-ray total scattering coupled with pair distribution function analysis produces unique structural fingerprints from amorphous and nanostructured phases of the pharmaceuticals carbamazepine and indomethacin. The advantages of such facility-based experiments over laboratory-based ones are discussed and the technique is illustrated with the characterisation of a melt-quenched sample of carbamazepine as a nanocrystalline (4.5 nm domain diameter) version of form III.

Graphical abstract: Characterisation of amorphous and nanocrystalline molecular materials by total scattering

Supplementary files

Additions and corrections

Article information

Article type
Communication
Submitted
28 Jul 2009
Accepted
07 Oct 2009
First published
19 Oct 2009

CrystEngComm, 2010,12, 1366-1368

Characterisation of amorphous and nanocrystalline molecular materials by total scattering

S. J. L. Billinge, T. Dykhne, P. Juhás, E. Božin, R. Taylor, A. J. Florence and K. Shankland, CrystEngComm, 2010, 12, 1366 DOI: 10.1039/B915453A

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